Формотерол-натив Капсулы, 30 шт, 12 мкг/доза

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href=\"https://www.vidal.ru/drugs/pharm-group/142\"\u003eБета2-адреномиметик селективный\u003c/a\u003e"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Бета-адреномиметик."}},{"type":"paragraph","data":{"text":"Действует преимущественно на β2-адренорецепторы."}},{"type":"paragraph","data":{"text":"Оказывает бронхолитическое действие, купирует и предупреждает бронхоспазм."}},{"type":"paragraph","data":{"text":"Ингибирует высвобождение гистамина, лейкотриенов и простагландина D2 из тучных клеток, базофилов и сенсибилизированных клеток бронхоальвеолярного дерева."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"list","data":{"style":"ordered","items":["Профилактика бронхоспазма, вызываемого вдыханием аллергенов, холодным воздухом или физической нагрузкой в качестве дополнения к терапии ингаляционными глюкокортикостероидами.","Профилактика и лечение нарушений бронхиальной проходимости у больных с хронической обструктивной болезнью легких (ХОБЛ), при наличии как обратимой, так и необратимой бронхиальной обструкции, хроническим бронхитом и эмфиземой легких.","Профилактика и лечение нарушений бронхиальной проходимости у больных с бронхиальной астмой (БА) в качестве дополнения к терапии ингаляционными глюкокортикостероидами."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["Возраст до 18 лет.","Кормление грудью.","Повышенная чувствительность и/или непереносимость любого из компонентов препарата.","Редкие наследственные заболевания, такие как непереносимость лактозы, дефицит лактазы или глюкозо-галактозная мальабсорбция."]}},{"type":"paragraph","data":{"text":"Если у Вас имеется одно из перечисленных заболевании, перед применением препарата обязательно проконсультируйтесь с врачом."}},{"type":"paragraph","data":{"text":"Соблюдение особой осторожности при применении препарата Формотерол-натив (особенно с точки зрения снижения дозы) и тщательное наблюдение за пациентами требуется при наличии следующих сопутствующих заболеваний: ИБС; нарушения сердечного ритма и проводимости, особенно AV-блокада III степени; тяжелая сердечная недостаточность; идиоматический гипертрофический субаортальный стеноз; тяжелая степень артериальной гипертензии; аневризма любой локализации; феохромоцитома; кетоацидоз; гипертрофическая обструктивная кардиомиопатия; тиреотоксикоз; известное или подозреваемое удлинение интервала QTc (QT корригированный >0.44 сек)."}},{"type":"paragraph","data":{"text":"Учитывая гипергликемический эффект, свойственный бета2-адреномиметикам, у больных сахарным диабетом, принимающим Формотерол-натив, рекомендуется дополнительный регулярный контроль концентрации глюкозы в крови."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Формотерол-натив предназначен для ингаляционного применения у пациентов в 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Препарат не предназначен для приема внутрь."}},{"type":"paragraph","data":{"text":"Доза препарата Формотерол-натив подбирается индивидуально в зависимости от потребностей пациента. Следует использовать наименьшую дозу, обеспечивающую терапевтический эффект. При достижении контроля симптомов бронхиальной астмы на фоне терапии препаратом Формотерол-натив, необходимо рассмотреть возможность постепенного снижения дозы препарата. Снижение дозы препарата Формотерол-натив проводят под регулярным врачебным контролем состояния пациента."}},{"type":"paragraph","data":{"text":"Пpeпapaт представляет собой капсулы с порошком для ингаляций, которые следует применять только с помощью специального устройства - ингалятора \"Инхалер CDM®\", который входит в комплект упаковки."}},{"type":"paragraph","data":{"text":"Бронхиальная астма"}},{"type":"paragraph","data":{"text":"Доза препарата Формотерол-натив для регулярной поддерживающей терапии (составляет 12-24 мкг (содержимое 1-2 капс.) 2 раза/сут."}},{"type":"paragraph","data":{"text":"Формотерол-натив следует применять только в качестве дополнительной терапии к ингаляционным ГКС. Не следует превышать максимальную рекомендованную дозу препарата 48 мкг/сут (содержимое 4 капс.)."}},{"type":"paragraph","data":{"text":"Учитывая, что максимальная суточная доза препарата Формотерол-натив составляет 48 мкг, при необходимости дополнительно можно применить 12-24 мкг/сут для облегчения симптомов бронхиальной астмы."}},{"type":"paragraph","data":{"text":"Если потребность в применении дополнительных доз препарата Формотерол-натив перестает быть эпизодической (например, становится чаще, чем 2 дня в неделю), это может указывать на ухудшение течения бронхиальной астмы, следует обратиться к врачу. На фоне обострения бронхиальной астмы не следует начинать лечение препаратом Формотерол-натив или изменять дозировку препарата."}},{"type":"paragraph","data":{"text":"Формотерол-натив не следует применять для купирования острых приступов бронхиальной астмы."}},{"type":"paragraph","data":{"text":"Профилактика бронхоспазма, вызываемого физической нагрузкой или неизбежным воздействием известного аллергена"}},{"type":"paragraph","data":{"text":"Следует применять Формотерол-натив дозе 12 мкг (содержимое 1 капс.) за 15 мин до предполагаемого контакта с аллергеном или до нагрузки. Дополнительные ингаляции препарата не должны проводиться в течение последующих 12 ч."}},{"type":"paragraph","data":{"text":"Профилактика тяжелых бронхоспазмов"}},{"type":"paragraph","data":{"text":"Больным с тяжелыми бронхоспазмами в анамнезе может потребоваться однократная ингаляция в дозе 24 мкг (содержимое 2 капс.)."}},{"type":"paragraph","data":{"text":"ХОБЛ"}},{"type":"paragraph","data":{"text":"Доза препарата Формотсрол-натив для регулярной поддерживающей терапии ХОБЛ составляет 12-24 мкг (содержимое 1-2 капсул) 2 раза/сут."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Нежелательные реакции распределены в соответствии с частотой возникновения. Для оценки частоты использованы следующие критерии: очень часто (>1/10), часто (от 1/100 до 1/10), нечасто (от 1/1000 до 1/100), редко (от 1/10000 до 1/1000), очень редко ("}},{"type":"paragraph","data":{"text":"Инфекционные и паразитарные заболевания: часто - фарингит, острая респираторная вирусная инфекция."}},{"type":"paragraph","data":{"text":"Нарушения со стороны иммунной системы: очень редко – анафилактические реакции, крапивница, ангионевротический отек (отек Квинке), зуд, сыпь."}},{"type":"paragraph","data":{"text":"Нарушения со стороны обмена веществ и питания: очень редко - метаболический ацидоз."}},{"type":"paragraph","data":{"text":"Нарушения психики: нечасто - ажитация, тревога, повышенная возбудимость, бессонница; очень редко - повышенная утомляемость."}},{"type":"paragraph","data":{"text":"Нарушения со стороны нервной системы: часто - головная боль, тремор; нечасто-головокружение; очень редко – изменение вкусовых ощущений."}},{"type":"paragraph","data":{"text":"Нарушения со стороны сердца: часто - ощущение сердцебиения, боль в груди; нечасто – тахикардия; очень редко - периферические отеки;стенокардия, нарушение сердечного ритма (в т.ч. фибрилляция предсердий, желудочковые экстрасистолы, тахиаритмия)."}},{"type":"paragraph","data":{"text":"Нарушения со стороны сосудов: очень редко - снижение артериального давления (гипотензия), повышение артериального давления (гипертензия)."}},{"type":"paragraph","data":{"text":"Нарушения со стороны дыхательной системы, органов грудной клетки и средостения: часто – синусит, увеличение продукции мокроты; нечасто - бронхоспазм, включая парадоксальный, дисфония; очень редко - кашель."}},{"type":"paragraph","data":{"text":"Нарушения со стороны желудочно-кишечного тракта: нечасто – сухость слизистой оболочки полости рта; очень редко - тошнота."}},{"type":"paragraph","data":{"text":"Нарушения со стороны скелетно-мышечной и соединительной ткани: часто - боли в спине, судороги ног; нечасто – мышечный спазм,миалгии."}},{"type":"paragraph","data":{"text":"Общие расстройства и нарушения в месте введения: часто - лихорадка; нечасто - раздражение слизистой оболочки глотки и гортани."}},{"type":"paragraph","data":{"text":"Лабораторные и инструментальные данные: нечасто - уплощение или инверсия зубца Т, депрессия сегмента ST, удлинение интервала QT на электрокардиограмме; очень редко - гипокалиемия, гипергликемия."}},{"type":"paragraph","data":{"text":"Если любые из указанных в инструкции побочных реакций усугубляются, или Вы заметили любые другие побочные реакции, не указанные в инструкции, сообщите об этом врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы: передозировка формотеролом, вероятно, может привести к развитию явлений, характерных для передозировки бета2-адрсномиметиками или усилению проявления побочных действий: боль за грудиной, ощущение сердцебиения, тахикардия до 200 уд./мин, желудочковые аритмии, повышение пли понижение АД, сухость во рту, тошнота, рвота, головная боль, головокружение, тремор, нервозность, слабость, тревога, сонливость, метаболический ацидоз, гипокалиемия, гипергликемия, судороги. Как и для всех ингаляционных бета2-адреномиметиков, при передозировке формотеролом, возможна остановка сердца и смертельный исход."}},{"type":"paragraph","data":{"text":"Лечение: показано проведение поддерживающей и симптоматической терапии. В серьезных случаях необходима госпитализация."}},{"type":"paragraph","data":{"text":"Может рассматриваться применение кардиоселективных бета2-адреноблокаторов, но только под тщательным медицинским наблюдением при условии соблюдения чрезвычайной осторожности, т.к. использование таких средств может вызвать бронхоспазм. Рекомендован контроль показателей сердечной деятельности."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Препарат Формотерол-натив, так же как и другие β2-адреномиметики, следует с осторожностью назначать пациентам, получающим такие лекарственные средства, как: хинидин, дизопирамид, прокаинамид, фенотиазины, макролиды, ингибиторы моноаминооксидазы (МАО), трициклические антидепрессанты, антигистаминные препараты, а также другие препараты, о которых известно, что они удлиняют интервал QT, так как в этих случаях действие адреностимуляторов на сердечно-сосудистую систему может усиливаться и повышается риск возникновения желудочковых аритмий."}},{"type":"paragraph","data":{"text":"Одновременное применение других симпатомиметических средств может приводить к усугублению побочных реакций препарата Формотерол-натив."}},{"type":"paragraph","data":{"text":"Одновременное применение производных ксантина, глюкокортикостероидов или диуретиков может усиливать потенциальное гипокалиемическое действие препарата Формотерол-натив."}},{"type":"paragraph","data":{"text":"У пациентов, получающих анестезию с использованием галогенизированных углеводородов, повышается риск развития аритмий."}},{"type":"paragraph","data":{"text":"Препараты, относящиеся к β2-адреноблокаторам, могут ослаблять действие препарата Формотерол-натив и приводить к серьезному бронхоспазму у больных бронхиальной астмой. В связи с этим не следует применять препарат Формотерол-натив совместно с β2-адреноблокаторами (включая глазные капли), если только к использованию такой комбинации препаратов не вынуждают какие-либо чрезвычайные причины."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Противовоспалительная терапия"}},{"type":"paragraph","data":{"text":"У пациентов с бронхиальной астмой Формотерол-натив следует использовать только в качестве дополнительного лечения при недостаточном контроле симптомов на фоне монотерапии ингаляционными ГКС или при тяжелой форме заболевания, требующей применения комбинации ингаляционного ГКС и агониста β2-адренорецепторов длительного действия. Нельзя применять Формотерол-натив с другими агонистами β2-адренорецепторов длительного действия."}},{"type":"paragraph","data":{"text":"При назначении препарата Формотерол-натив необходимо оценить состояние пациентов в отношении адекватности той противовоспалительной терапии, которую они получают. После начала лечения препаратом Формотерол-натив пациентам следует рекомендовать продолжать противовоспалительную терапию без изменений, даже в том случае, если будет отмечено улучшение."}},{"type":"paragraph","data":{"text":"Для купирования острого приступа бронхиальной астмы следует применять агонисты β2-адренорецепторов. При внезапном ухудшении состояния пациенты должны немедленно обращаться за медицинской помощью."}},{"type":"paragraph","data":{"text":"Гипокалиемия"}},{"type":"paragraph","data":{"text":"Следствием терапии бета2-адреномиметиками, включая Формотерол-натив, может быть развитие потенциально серьезной гипокалиемии. Гипокалиемия может увеличить риск развития аритмий. Т.к. данное действие препарата Формотерол-натив может быть усилено гипоксией и сопутствующим лечением, особую осторожность следует соблюдать у больных бронхиальной астмой тяжелого течения. В этих случаях рекомендуется регулярный контроль концентрации калия в сыворотке крови."}},{"type":"paragraph","data":{"text":"Парадоксальный бронхоспазм"}},{"type":"paragraph","data":{"text":"Как и другие ингаляционные препараты, Формотерол-натив может вызвать парадоксальный бронхоспазм. В этом случае, следует немедленно отменить препарат и назначить альтернативное лечение."}},{"type":"paragraph","data":{"text":"Применение формотерола в дозе, превышающей 54 мкг/сут (свыше 4 ингаляций), может привести к положительным результатам тестов на допинг."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Влияние на способность управлять автотранспортом и другими транспортными средствами, на работу с движущимися механизмами"}},{"type":"paragraph","data":{"text":"Данные о влиянии препарата Формотерол-натив на способность к вождению автотранспорта и управлению механизмами отсутствуют. В случае развития таких побочных реакций, как головокружение, тремор, судороги или мышечный спазм необходимо воздержаться от вождения автотранспорта и управления механизмами, а также от занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы с порошком для ингаляций"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света месте при температуре не выше 25С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не применять но истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.eapteka.ru/goods/manufacturer/nativa/\"\u003eНатива, Россия\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"Бета-адреномиметик. Действует преимущественно на β2-адренорецепторы. Оказывает бронхолитическое действие, купирует и предупреждает бронхоспазм. Ингибирует высвобождение гистамина, лейкотриенов и простагландина D2 из тучных клеток, базофилов и сенсибилизированных клеток бронхоальвеолярного дерева.","substance":[{"id":570,"title":"Формотерол","title_latin":"Formoterolum","slug":"formoterol_570"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Формотерол-натив - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/70757/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/70757/share_default/"}},"diseases":[{"id":"825","title":"Другая хроническая обструктивная легочная болезнь","slug":"825-drugaya_hronicheskaya_obstruktivnaya_legochnaya_bolezn"},{"id":"826","title":"Астма","slug":"826-astma"}],"other_packages":[{"id":103543,"title":"Формотерол-Натив","subtitle":{"full":"Капсулы, коробка, 60 шт, 12 мкг/доза, для ингаляций, с порошком в комплекте с устройством для ингаляций","short":"Капсулы, 60 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