ТЕРАФЛЮ ЭКСТРА - мощная сила против 7 основных симптомов гриппа и простуды!*. Применяется для симптоматической терапии инфекционно-воспалительных заболеваний: ОРВИ, в том числе грипп и «простуда», проявлениями которых являются:
Комбинированный препарат, действие которого обусловлено входящими в его состав компонентами. Оказывает жаропонижающее, анальгезирующее, сосудосуживающее действие, устраняет симптомы "простуды". Сужает сосуды и устраняет отек слизистой оболочки полости носа и носоглотки.
Парацетамол оказывает обезболивающее и жаропонижающее действие путем подавления синтеза простагландинов в ЦНС. Не влияет на функцию тромбоцитов и гемостаз.
Фенирамин - противоаллергическое средство, блокатор гистаминовых H1-рецепторов. Устраняет аллергические симптомы, в умеренной степени оказывает седативный эффект, а также проявляет антимускариновую активность.
Фенилэфрин - альфа1-адреномиметик, вызывает сужение сосудов, устраняет отечность и гиперемию слизистой оболочки полости носа.
Показания к применению
симптоматическое лечение инфекционно-воспалительных заболеваний (ОРВИ, в т.ч. гриппа), сопровождающихся высокой температурой, ознобом, головной болью, насморком, заложенностью носа, чиханьем, болями в мышцах.
Противопоказания
повышенная чувствительность к компонентам препарата;
одновременный или в течение предшествующих 2 недель прием ингибиторов МАО;
одновременный прием трициклических антидепрессантов, бета-адреноблокаторов, других симпатомиметиков;
беременность;
период грудного вскармливания;
детский возраст до 12 лет.
С осторожностью
при выраженном атеросклерозе коронарных артерий, сердечно-сосудистых заболеваниях, остром гепатите, гемолитической анемии, бронхиальной астме, тяжелых заболеваниях печени или почек, гиперплазии предстательной железы, затруднении мочеиспускания вследствие гипертрофии предстательной железы, заболеваниях крови, дефиците глюкозо-6-фосфатдегидрогеназы, врожденной гипербилирубинемии (синдромы Жильбера, Дубина-Джонсона и Ротора), при истощении, обезвоживании, пилородуоденальной обструкции, стенозирующей язве желудка и/или двенадцатиперстной кишки, эпилепсии, при одновременном приеме препаратов, способных отрицательно влиять на печень.
Применение при беременности и в период грудного вскармливания
Не рекомендуется применять препарат при беременности и грудном вскармливании в связи с отсутствием данных по безопасному применению препарата у данной категории пациентов.
Способ применения и дозы
Внутрь. Содержимое одного пакетика растворяют в 1 стакане (250 мл) горячей, но не кипящей воды. Принимают в горячем виде. Повторную дозу можно принимать через каждые 4-6 ч (не более 3-4 доз в течение 24 ч).
ТераФлю Экстра можно применять в любое время суток, но наилучший эффект приносит прием препарата перед сном, на ночь. Если не наблюдается облегчения симптомов в течение 3 дней после начала приема препарата, необходимо обратиться к врачу.
Не следует применять ТераФлю Экстра более 5 дней.
У пациентов с нарушением функции печени или синдромом Жильбера необходимо уменьшить дозу или увеличить интервал между приемами.
При почечной недостаточности тяжелой степени (КК<10 мл/мин) интервал между приемами должен составлять не менее 8 ч.
У пациентов пожилого возраста коррекция дозы не требуется.
Побочное действие
Определение частоты побочных эффектов: очень часто (≥1/10), часто (≥1/100 и <1/10), нечасто (≥1/1000 и <1/100), редко (≥1/10 000 и <1/1000), очень редко (<1/10 000), включая отдельные сообщения.
Со стороны системы кроветворения: очень редко - тромбоцитопения, агранулоцитоз, лейкопения, панцитопения.
Со стороны иммунной системы: редко - повышенная чувствительность, ангионевротический отек; неизвестно - анафилактическая реакция, синдром Стивенса-Джонсона, токсический эпидермальный некролиз.
Со стороны нервной системы: часто - сонливость; редко - головокружение, головная боль.
Нарушения психики: редко - повышенная возбудимость, нарушение сна.
Со стороны органа зрения: редко - мидриаз, парез аккомодации, повышение внутриглазного давления.
Со стороны сердечно-сосудистой системы: редко - тахикардия, ощущение сердцебиения, артериальная гипертензия.
Со стороны пищеварительной системы: часто - тошнота, рвота; редко - сухость во рту, запор, дискомфорт в желудке, диарея.
Со стороны печени и желчевыводящих путей: редко - повышение активности печеночных трансаминаз.
Со стороны кожи и подкожных тканей: редко - кожная сыпь, зуд, эритема, крапивница.
Со стороны мочевыделительной системы: редко - затруднение мочеиспускания.
Общие реакции: редко - недомогание.
Если любые из указанных выше побочных эффектов усугубляются и появляются любые другие побочные эффекты, пациент должен обратиться к врачу.
Передозировка
Симптомы передозировки обусловлены в основном парацетамолом.
Парацетамол
Симптомы: в основном проявляются после приема 10-15 г парацетамола. В тяжелых случаях передозировки парацетамол оказывает гепатотоксическое действие, в т.ч. может вызвать некроз печени. Также передозировка может вызвать необратимую нефропатию и необратимое поражение печени. Выраженность передозировки зависит от дозы, поэтому пациентов следует предупреждать о запрете одновременного приема других препаратов, содержащих парацетамол. Выражен риск отравления особенно у пациентов пожилого возраста, у детей, у пациентов с заболеваниями печени, в случаях хронического алкоголизма, у пациентов с истощением и у пациентов, принимающих индукторы микросомальных ферментов печени.
Передозировка парацетамола может привести к печеночной недостаточности, энцефалопатии, коме и смерти.
Симптомы передозировки парацетамолом в первые 24 ч: бледность кожных покровов, тошнота, рвота, анорексия, судороги. Боль в животе может быть первым признаком поражения печени и обычно не проявляется в течение 24-48 ч и иногда может проявиться позже, через 4-6 дней. Повреждение печени проявляется в максимальной степени по истечении 72-96 часов после приема препарата. Также может появиться нарушение метаболизма глюкозы и метаболический ацидоз. Даже при отсутствии поражения печени может развиться острая почечная недостаточность и острый тубулярный некроз. Сообщалось о случаях сердечной аритмии и развития панкреатита.
Лечение: введение N-ацетилцистеина в/в или перорально в качестве антидота, промывание желудка, прием внутрь метионина могут оказывать положительный эффект, по крайней мере, в течение 48 ч после передозировки. Рекомендован прием активированного угля, мониторинг дыхания и кровообращения. В случае развития судорог возможно назначение диазепама.
Фенирамин и фенилэфрин
Симптомы: сонливость, к которой в дальнейшем присоединяется беспокойство (особенно у детей), зрительные нарушения, сыпь, тошнота, рвота, головная боль, повышенная возбудимость, головокружение, бессонница, нарушения кровообращения, кома, судороги, изменения поведения, повышение АД и брадикардия. При передозировке фенирамина сообщалось о случаях атропиноподобного "психоза".
Лечение: специфический антидот отсутствует. Необходимы обычные меры оказания помощи, включающие назначение активированного угля, солевых слабительных, мер по поддержке сердечной и дыхательной функций. Не следует назначать психостимулирующие средства (метилфенидат) из-за опасности возникновения судорог. При артериальной гипотензии возможно применение вазопрессорных препаратов.
В случае повышения АД возможно в/в введение альфа-адреноблокаторов. При развитии судорог вводить диазепам.
Взаимодействие с другими лекарственными средствами
Риск гепатотоксического действия парацетамола повышается при одновременном применении барбитуратов, фенитоина, фенобарбитала, карбамазепина, рифампицина, изониазида, зидовудина и других индукторов микросомальных ферментов печени.
При длительном регулярном применении парацетамола возможно усиление антикоагулянтного эффекта варфарина и других кумаринов, при этом увеличивается риск кровотечения. Единичное применение парацетамола не оказывает существенного влияния.
Метоклопрамид повышает скорость всасывания парацетамола и уменьшает время достижения его Cmax в плазме крови. Аналогичным образом, домперидон может привести к увеличению скорости абсорбции парацетамола.
Парацетамол может приводить к увеличению T1/2 хлорамфеникола.
Парацетамол способен уменьшать биодоступность ламотриджина, при этом возможно уменьшение эффективности ламотриджина вследствие индукции его метаболизма в печени.
Абсорбция парацетамола может быть снижена при одновременном применении с колестирамином, но снижение всасывания незначительно, если колестирамин принимают на час позже.
Регулярное применение парацетамола одновременно с зидовудином может вызвать нейтропению и повышать риск повреждения печени.
Пробенецид влияет на метаболизм парацетамола. У пациентов, одновременно применяющих пробенецид, дозу парацетамола следует уменьшить.
Гепатотоксичность парацетамола усиливается при длительном чрезмерном употреблении этанола (алкоголя).
Парацетамол может повлиять на результаты теста по определению мочевой кислоты с использованием преципитирующего реагента фосфовольфрамата.
Фенирамин
Возможно усиление влияния других веществ на ЦНС (например, ингибиторов МАО, трициклических антидепрессантов, алкоголя, противопаркинсонических препаратов, барбитуратов, транквилизаторов и наркотических средств). Фенирамин может ингибировать действие антикоагулянтов.
Фенилэфрин
Терафлю Экстра противопоказан пациентам, которые получают или получали ингибиторы МАО в течение последних 2 недель. Фенилэфрин может потенцировать действие ингибиторов МАО и вызвать гипертонический криз.
Одновременное применение фенилэфрина с другими симпатомиметическими препаратами или трициклическими антидепрессантами (например, амитриптилином) может привести к увеличению риска нежелательных реакций со стороны сердечно-сосудистой системы.
Фенилэфрин может снижать эффективность бета-адреноблокаторов и других антигипертензивных препаратов (например, дебризохина, гуанетидина, резерпина, метилдопы). Возможно повышение риска артериальной гипертензии и других побочных эффектов со стороны сердечно-сосудистой системы.
Одновременное применение фенилэфрина с дигоксином и сердечными гликозидами может повышать риск нарушения ритма сердца или инфаркта миокарда.
Одновременное применение фенилэфрина с алкалоидами спорыньи (эрготамин и метисергид) может увеличить риск эрготизма.
Особые указания
Во избежание токсического поражения печени препарат не следует сочетать с применением алкогольных напитков.
Пациентам следует обратиться к врачу, если:
наблюдается бронхиальная астма, эмфизема или хронический бронхит;
симптомы не проходят в течение 5 дней пли сопровождаются тяжелой лихорадкой, продолжающейся в течение 3 дней, сыпью или постоянной головной болью.
Это могут быть признаки более серьезных нарушений.
Терафлю Экстра содержит:
сахарозы 12.6 г на пакетик. Это следует принимать во внимание у пациентов с сахарным диабетом. Пациентам с такими редкими наследственными проблемами, как непереносимость фруктозы, глюкозо-галактозной мальабсорбцией или недостаточностью сахаразы-изомальтазы, не следует принимать Терафлю Экстра;
краситель солнечный закат желтый (Е110). Может вызвать аллергические реакции;
натрия 42.2 мг на пакетик. Это должно быть принято во внимание у пациентов, соблюдающих диету с ограничением натрия.
Не следует использовать препарат из поврежденных пакетиков.
Влияние на способность управлять автомобилем и движущимися механизмами
Терафлю Экстра может вызывать сонливость, поэтому во время лечения не рекомендуется управлять транспортными средствами или заниматься другими видами деятельности требующими концентрации внимания и высокой скорости психомоторных реакций.
Форма выпуска
Порошок для приготовления раствора для приема внутрь (лимонный) сыпучий, содержащий гранулы белого и желтого цвета, со специфическим запахом, допускается наличие мягких комков.
Условия хранения
Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Устраняет аллергические симптомы, в умеренной степени оказывает седативный эффект, а также проявляет антимускариновую активность."}},{"type":"paragraph","data":{"text":"\u003ci\u003eФенилэфрин\u003c/i\u003e - альфа\u003csub\u003e1\u003c/sub\u003e-адреномиметик, вызывает сужение сосудов, устраняет отечность и гиперемию слизистой оболочки полости носа."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"list","data":{"style":"ordered","items":["симптоматическое лечение инфекционно-воспалительных заболеваний (ОРВИ, в т.ч. гриппа), сопровождающихся высокой температурой, ознобом, головной болью, насморком, заложенностью носа, чиханьем, болями в мышцах."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["повышенная чувствительность к компонентам препарата;","тяжелые сердечно-сосудистые заболевания;","артериальная гипертензия;","портальная гипертензия;","сахарный диабет;","гипертиреоз;","закрытоугольная глаукома;","феохромоцитома;","алкоголизм;","дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция;","одновременный или в течение предшествующих 2 недель прием ингибиторов МАО;","одновременный прием трициклических антидепрессантов, бета-адреноблокаторов, других симпатомиметиков;","беременность;","период грудного вскармливания;","детский возраст до 12 лет."]}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"при выраженном атеросклерозе коронарных артерий, сердечно-сосудистых заболеваниях, остром гепатите, гемолитической анемии, бронхиальной астме, тяжелых заболеваниях печени или почек, гиперплазии предстательной железы, затруднении мочеиспускания вследствие гипертрофии предстательной железы, заболеваниях крови, дефиците глюкозо-6-фосфатдегидрогеназы, врожденной гипербилирубинемии (синдромы Жильбера, Дубина-Джонсона и Ротора), при истощении, обезвоживании, пилородуоденальной обструкции, стенозирующей язве желудка и/или двенадцатиперстной кишки, эпилепсии, при одновременном приеме препаратов, способных отрицательно влиять на печень."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Не рекомендуется применять препарат при беременности и грудном вскармливании в связи с отсутствием данных по безопасному применению препарата у данной категории пациентов."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь. Содержимое одного пакетика растворяют в 1 стакане (250 мл) горячей, но не кипящей воды. Принимают в горячем виде. Повторную дозу можно принимать через каждые 4-6 ч (не более 3-4 доз в течение 24 ч)."}},{"type":"paragraph","data":{"text":"ТераФлю Экстра можно применять в любое время суток, но наилучший эффект приносит прием препарата перед сном, на ночь. Если не наблюдается облегчения симптомов в течение 3 дней после начала приема препарата, необходимо обратиться к врачу."}},{"type":"paragraph","data":{"text":"Не следует применять ТераФлю Экстра более 5 дней."}},{"type":"paragraph","data":{"text":"У \u003cb\u003eпациентов с нарушением функции печени или синдромом Жильбера\u003c/b\u003e необходимо уменьшить дозу или увеличить интервал между приемами."}},{"type":"paragraph","data":{"text":"При \u003cb\u003eпочечной недостаточности тяжелой степени (КК<10 мл/мин)\u003c/b\u003e интервал между приемами должен составлять не менее 8 ч."}},{"type":"paragraph","data":{"text":"У \u003cb\u003eпациентов пожилого возраста\u003c/b\u003e коррекция дозы не требуется."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Определение частоты побочных эффектов: очень часто (≥1/10), часто (≥1/100 и <1/10), нечасто (≥1/1000 и <1/100), редко (≥1/10 000 и <1/1000), очень редко (<1/10 000), включая отдельные сообщения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны системы кроветворения:\u003c/i\u003e очень редко - тромбоцитопения, агранулоцитоз, лейкопения, панцитопения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны иммунной системы: \u003c/i\u003eредко - повышенная чувствительность, ангионевротический отек; неизвестно - анафилактическая реакция, синдром Стивенса-Джонсона, токсический эпидермальный некролиз."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны нервной системы: \u003c/i\u003eчасто - сонливость; редко - головокружение, головная боль."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения психики: \u003c/i\u003eредко - повышенная возбудимость, нарушение сна."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органа зрения:\u003c/i\u003e редко - мидриаз, парез аккомодации, повышение внутриглазного давления."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны сердечно-сосудистой системы: \u003c/i\u003eредко - тахикардия, ощущение сердцебиения, артериальная гипертензия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы: \u003c/i\u003eчасто - тошнота, рвота; редко - сухость во рту, запор, дискомфорт в желудке, диарея."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны печени и желчевыводящих путей: \u003c/i\u003eредко - повышение активности печеночных трансаминаз."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны кожи и подкожных тканей: \u003c/i\u003eредко - кожная сыпь, зуд, эритема, крапивница."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны мочевыделительной системы:\u003c/i\u003e редко - затруднение мочеиспускания."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие реакции:\u003c/i\u003e редко - недомогание."}},{"type":"paragraph","data":{"text":"Если любые из указанных выше побочных эффектов усугубляются и появляются любые другие побочные эффекты, пациент должен обратиться к врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы передозировки обусловлены в основном парацетамолом."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПарацетамол\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы:\u003c/i\u003e в основном проявляются после приема 10-15 г парацетамола. В тяжелых случаях передозировки парацетамол оказывает гепатотоксическое действие, в т.ч. может вызвать некроз печени. Также передозировка может вызвать необратимую нефропатию и необратимое поражение печени. Выраженность передозировки зависит от дозы, поэтому пациентов следует предупреждать о запрете одновременного приема других препаратов, содержащих парацетамол. Выражен риск отравления особенно у пациентов пожилого возраста, у детей, у пациентов с заболеваниями печени, в случаях хронического алкоголизма, у пациентов с истощением и у пациентов, принимающих индукторы микросомальных ферментов печени."}},{"type":"paragraph","data":{"text":"Передозировка парацетамола может привести к печеночной недостаточности, энцефалопатии, коме и смерти."}},{"type":"paragraph","data":{"text":"Симптомы передозировки парацетамолом в первые 24 ч: бледность кожных покровов, тошнота, рвота, анорексия, судороги. Боль в животе может быть первым признаком поражения печени и обычно не проявляется в течение 24-48 ч и иногда может проявиться позже, через 4-6 дней. Повреждение печени проявляется в максимальной степени по истечении 72-96 часов после приема препарата. Также может появиться нарушение метаболизма глюкозы и метаболический ацидоз. Даже при отсутствии поражения печени может развиться острая почечная недостаточность и острый тубулярный некроз. Сообщалось о случаях сердечной аритмии и развития панкреатита."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение:\u003c/i\u003e введение N-ацетилцистеина в/в или перорально в качестве антидота, промывание желудка, прием внутрь метионина могут оказывать положительный эффект, по крайней мере, в течение 48 ч после передозировки. Рекомендован прием активированного угля, мониторинг дыхания и кровообращения. В случае развития судорог возможно назначение диазепама."}},{"type":"paragraph","data":{"text":"\u003ci\u003eФенирамин и фенилэфрин\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы:\u003c/i\u003e сонливость, к которой в дальнейшем присоединяется беспокойство (особенно у детей), зрительные нарушения, сыпь, тошнота, рвота, головная боль, повышенная возбудимость, головокружение, бессонница, нарушения кровообращения, кома, судороги, изменения поведения, повышение АД и брадикардия. При передозировке фенирамина сообщалось о случаях атропиноподобного \"психоза\"."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение:\u003c/i\u003e специфический антидот отсутствует. Необходимы обычные меры оказания помощи, включающие назначение активированного угля, солевых слабительных, мер по поддержке сердечной и дыхательной функций. Не следует назначать психостимулирующие средства (метилфенидат) из-за опасности возникновения судорог. При артериальной гипотензии возможно применение вазопрессорных препаратов."}},{"type":"paragraph","data":{"text":"В случае повышения АД возможно в/в введение альфа-адреноблокаторов. При развитии судорог вводить диазепам."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eПарацетамол\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Усиливает эффекты ингибиторов МАО, седативных средств, этанола."}},{"type":"paragraph","data":{"text":"Риск гепатотоксического действия парацетамола повышается при одновременном применении барбитуратов, фенитоина, фенобарбитала, карбамазепина, рифампицина, изониазида, зидовудина и других индукторов микросомальных ферментов печени."}},{"type":"paragraph","data":{"text":"При длительном регулярном применении парацетамола возможно усиление антикоагулянтного эффекта варфарина и других кумаринов, при этом увеличивается риск кровотечения. Единичное применение парацетамола не оказывает существенного влияния."}},{"type":"paragraph","data":{"text":"Метоклопрамид повышает скорость всасывания парацетамола и уменьшает время достижения его C\u003csub\u003emax\u003c/sub\u003e в плазме крови. Аналогичным образом, домперидон может привести к увеличению скорости абсорбции парацетамола."}},{"type":"paragraph","data":{"text":"Парацетамол может приводить к увеличению T\u003csub\u003e1/2 \u003c/sub\u003eхлорамфеникола."}},{"type":"paragraph","data":{"text":"Парацетамол способен уменьшать биодоступность ламотриджина, при этом возможно уменьшение эффективности ламотриджина вследствие индукции его метаболизма в печени."}},{"type":"paragraph","data":{"text":"Абсорбция парацетамола может быть снижена при одновременном применении с колестирамином, но снижение всасывания незначительно, если колестирамин принимают на час позже."}},{"type":"paragraph","data":{"text":"Регулярное применение парацетамола одновременно с зидовудином может вызвать нейтропению и повышать риск повреждения печени."}},{"type":"paragraph","data":{"text":"Пробенецид влияет на метаболизм парацетамола. У пациентов, одновременно применяющих пробенецид, дозу парацетамола следует уменьшить."}},{"type":"paragraph","data":{"text":"Гепатотоксичность парацетамола усиливается при длительном чрезмерном употреблении этанола (алкоголя)."}},{"type":"paragraph","data":{"text":"Парацетамол может повлиять на результаты теста по определению мочевой кислоты с использованием преципитирующего реагента фосфовольфрамата."}},{"type":"paragraph","data":{"text":"\u003ci\u003eФенирамин\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Возможно усиление влияния других веществ на ЦНС (например, ингибиторов МАО, трициклических антидепрессантов, алкоголя, противопаркинсонических препаратов, барбитуратов, транквилизаторов и наркотических средств). Фенирамин может ингибировать действие антикоагулянтов."}},{"type":"paragraph","data":{"text":"\u003ci\u003eФенилэфрин\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Терафлю Экстра противопоказан пациентам, которые получают или получали ингибиторы МАО в течение последних 2 недель. Фенилэфрин может потенцировать действие ингибиторов МАО и вызвать гипертонический криз."}},{"type":"paragraph","data":{"text":"Одновременное применение фенилэфрина с другими симпатомиметическими препаратами или трициклическими антидепрессантами (например, амитриптилином) может привести к увеличению риска нежелательных реакций со стороны сердечно-сосудистой системы."}},{"type":"paragraph","data":{"text":"Фенилэфрин может снижать эффективность бета-адреноблокаторов и других антигипертензивных препаратов (например, дебризохина, гуанетидина, резерпина, метилдопы). Возможно повышение риска артериальной гипертензии и других побочных эффектов со стороны сердечно-сосудистой системы."}},{"type":"paragraph","data":{"text":"Одновременное применение фенилэфрина с дигоксином и сердечными гликозидами может повышать риск нарушения ритма сердца или инфаркта миокарда."}},{"type":"paragraph","data":{"text":"Одновременное применение фенилэфрина с алкалоидами спорыньи (эрготамин и метисергид) может увеличить риск эрготизма."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Во избежание токсического поражения печени препарат не следует сочетать с применением алкогольных напитков."}},{"type":"paragraph","data":{"text":"Пациентам следует обратиться к врачу, если:"}},{"type":"list","data":{"style":"ordered","items":["наблюдается бронхиальная астма, эмфизема или хронический бронхит;","симптомы не проходят в течение 5 дней пли сопровождаются тяжелой лихорадкой, продолжающейся в течение 3 дней, сыпью или постоянной головной болью."]}},{"type":"paragraph","data":{"text":"Это могут быть признаки более серьезных нарушений."}},{"type":"paragraph","data":{"text":"Терафлю Экстра содержит:"}},{"type":"list","data":{"style":"ordered","items":["сахарозы 12.6 г на пакетик. Это следует принимать во внимание у пациентов с сахарным диабетом. Пациентам с такими редкими наследственными проблемами, как непереносимость фруктозы, глюкозо-галактозной мальабсорбцией или недостаточностью сахаразы-изомальтазы, не следует принимать Терафлю Экстра;","краситель солнечный закат желтый (Е110). Может вызвать аллергические реакции;","натрия 42.2 мг на пакетик. Это должно быть принято во внимание у пациентов, соблюдающих диету с ограничением натрия."]}},{"type":"paragraph","data":{"text":"Не следует использовать препарат из поврежденных пакетиков."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":" Терафлю Экстра может вызывать сонливость, поэтому во время лечения не рекомендуется управлять транспортными средствами или заниматься другими видами деятельности требующими концентрации внимания и высокой скорости психомоторных реакций. "}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ci\u003e\u003cb\u003eПорошок для приготовления раствора для приема внутрь (лимонный) \u003c/b\u003e\u003c/i\u003eсыпучий, содержащий гранулы белого и желтого цвета, со специфическим запахом, допускается наличие мягких комков. "}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"Срок годности - 2 года."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Препарат отпускается без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/firm/4838\"\u003eГлаксоСмитКляйн Хелскер, АО\u003c/a\u003e (Россия) "}}]}],"source":null},"description_toggle":false,"short_description":"Комбинированный препарат, действие которого обусловлено входящими в его состав компонентами. Оказывает жаропонижающее, анальгезирующее, сосудосуживающее действие, устраняет симптомы \"простуды\". Сужает сосуды и устраняет отек слизистой оболочки полости носа и носоглотки.Парацетамолоказывает обезболивающее и жаропонижающее действие путем подавления синтеза простагландинов в ЦНС. Не влияет на функцию тромбоцитов и гемостаз.Фенирамин- противоаллергическое средство, блокатор гистаминовых H1-рецепторов. 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