Стоморджил/Stomorgil — комбинированный антибактериальный препарат, который применяется у собак и кошек при инфекционных заболеваниях ротовой полости — периодонте, стоматите, гингивите, пиорее.
СОСТАВ И ФОРМА ВЫПУСКА Препарат Стоморджил 10 в одной таблетке содержит спирамицин — 750000 МЕ и метронидазол — 125 мг, а также вспомогательные компоненты: гидроксид алюминия, сорбитол, белый декстрин и стеарат магния. По внешнему виду представляет собой таблетки желтого цвета. Расфасовывают по 10 таблеток в блистеры из ламинированной бумаги, вложенные по 2 штуки в картонную коробку.
ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА Действующие компоненты препарата — метронидазол и спиромецин проявляют синергизм действия в отношении широкого спектра патогенных микроорганизмов, в том числе и простейших. Спиромицин как природный антибиотик из группы макролидов способен обратимо связывается с рибосомами и подавлять синтез белка в микробной клетке. Активен в отношении Streptococcus spp. (в т.ч. Streptococcus pneumoniae), Staphylococcus aureus, Meningococcus spp., Bordetella spp., Corynebacterium spp., Listeria monocytogenes, Clostridium spp., Mycoplasma mycoides, Chlamydia spp., Leptospira interrogans, Campylobacter spp., Haemophilus spp., Bacteroides nodosus, Fusobacterium spp. и простейших: Toxoplasma gondii. Метронидазол нарушает дыхательные процессы в клетке, что вызывает гибель патогенных простейших. Кроме того, у некоторых видов анаэробов обладает способностью подавлять синтез ДНК и вызывать ее деструкцию. Активен в отношении грамположительных анаэробов: Clostridium spp., Eubacterium spp., Helicobacter pylori и грамотрицательных бактероидов и фузобактерий, а также простейших трихомонад. При пероральном применении препарат хорошо всасывается из желудочно-кишечного тракта (биодоступность около 100 %) и максимальная концентрация его компонентов в крови отмечается через 1,5 – 3 часа. По степени воздействия на организм теплокровных животных препарат относится к малоопасным веществам и в рекомендуемых дозах не оказывает резорбтивно-токсического, мутагенного и сенсибилизирующего действия.
ПОКАЗАНИЯ Назначают собакам и кошкам для лечения инфекций, вызванных микроорганизмами, чувствительными к спирамицину и метронидазолу, особенно в остром и подостром периоде течения заболевания. В комплексной терапии воспалительных заболеваний ротовой полости, в том числе стоматитов, гингивитов, пиореи и периодонтита.
ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ Таблетки Стоморджил 10 задают животным внутрь один раз в сутки из расчета 75000 МЕ спирамицина и 12,5 мг метронидазола на 1 кг веса животного, что соответствует одной таблетке Стоморджила 10 на 10 кг массы животного. Продолжительность курса лечения составляет 5 − 10 дней, в зависимости от индивидуальных особенностей организма и характера течения заболевания.
ПОБОЧНЫЕ ДЕЙСТВИЯ В очень редких случаях при повышенной индивидуальной чувствительности к компонентам препарата у животного могут наблюдаться аллергические реакции и рвота. При появлении указанных признаков применение препарата следует прекратить.
ПРОТИВОПОКАЗАНИЯ Повышенная индивидуальная чувствительность к компонентам препарата. Не рекомендуется использовать таблетки в измельченном виде, а также назначать с другими антибиотиками из группы макролидов.
ОСОБЫЕ УКАЗАНИЯ Особые меры предосторожности не предусмотрены. Препарат разрешен к применению у беременных и кормящих самок.
УСЛОВИЯ ХРАНЕНИЯ В сухом, защищенном от прямых солнечных лучей и недоступном для детей и животных месте при температуре от 0 до 25 °С. Срок годности — 3 года.
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По внешнему виду представляет собой таблетки желтого цвета. Расфасовывают по 10 таблеток в блистеры из ламинированной бумаги, вложенные по 2 штуки в картонную коробку."}},{"type":"paragraph","data":{"text":"ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА\u003cbr /\u003eДействующие компоненты препарата — метронидазол и спиромецин проявляют синергизм действия в отношении широкого спектра патогенных микроорганизмов, в том числе и простейших. Спиромицин как природный антибиотик из группы макролидов способен обратимо связывается с рибосомами и подавлять синтез белка в микробной клетке. Активен в отношении Streptococcus spp. (в т.ч. Streptococcus pneumoniae), Staphylococcus aureus, Meningococcus spp., Bordetella spp., Corynebacterium spp., Listeria monocytogenes, Clostridium spp., Mycoplasma mycoides, Chlamydia spp., Leptospira interrogans, Campylobacter spp., Haemophilus spp., Bacteroides nodosus, Fusobacterium spp. и простейших: Toxoplasma gondii. Метронидазол нарушает дыхательные процессы в клетке, что вызывает гибель патогенных простейших. Кроме того, у некоторых видов анаэробов обладает способностью подавлять синтез ДНК и вызывать ее деструкцию. Активен в отношении грамположительных анаэробов: Clostridium spp., Eubacterium spp., Helicobacter pylori и грамотрицательных бактероидов и фузобактерий, а также простейших трихомонад. При пероральном применении препарат хорошо всасывается из желудочно-кишечного тракта (биодоступность около 100 %) и максимальная концентрация его компонентов в крови отмечается через 1,5 – 3 часа. По степени воздействия на организм теплокровных животных препарат относится к малоопасным веществам и в рекомендуемых дозах не оказывает резорбтивно-токсического, мутагенного и сенсибилизирующего действия."}},{"type":"paragraph","data":{"text":"ПОКАЗАНИЯ\u003cbr /\u003eНазначают собакам и кошкам для лечения инфекций, вызванных микроорганизмами, чувствительными к спирамицину и метронидазолу, особенно в остром и подостром периоде течения заболевания. В комплексной терапии воспалительных заболеваний ротовой полости, в том числе стоматитов, гингивитов, пиореи и периодонтита."}},{"type":"paragraph","data":{"text":"ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ\u003cbr /\u003eТаблетки Стоморджил 10 задают животным внутрь один раз в сутки из расчета 75000 МЕ спирамицина и 12,5 мг метронидазола на 1 кг веса животного, что соответствует одной таблетке Стоморджила 10 на 10 кг массы животного. Продолжительность курса лечения составляет 5 − 10 дней, в зависимости от индивидуальных особенностей организма и характера течения заболевания."}},{"type":"paragraph","data":{"text":"ПОБОЧНЫЕ ДЕЙСТВИЯ\u003cbr /\u003eВ очень редких случаях при повышенной индивидуальной чувствительности к компонентам препарата у животного могут наблюдаться аллергические реакции и рвота. При появлении указанных признаков применение препарата следует прекратить."}},{"type":"paragraph","data":{"text":"ПРОТИВОПОКАЗАНИЯ\u003cbr /\u003eПовышенная индивидуальная чувствительность к компонентам препарата. Не рекомендуется использовать таблетки в измельченном виде, а также назначать с другими антибиотиками из группы макролидов."}},{"type":"paragraph","data":{"text":"ОСОБЫЕ УКАЗАНИЯ\u003cbr /\u003eОсобые меры предосторожности не предусмотрены. 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Активен в отношении грамположительных анаэробов: Clostridium spp., Eubacterium spp., Helicobacter pylori и грамотрицательных бактероидов и фузобактерий, а также простейших трихомонад. При пероральном применении препарат хорошо всасывается из желудочно-кишечного тракта (биодоступность около 100 %) и максимальная концентрация его компонентов в крови отмечается через 1,5 – 3 часа. По степени воздействия на организм теплокровных животных препарат относится к малоопасным веществам и в рекомендуемых дозах не оказывает резорбтивно-токсического, мутагенного и сенсибилизирующего действия. ПОКАЗАНИЯ Назначают собакам и кошкам для лечения инфекций, вызванных микроорганизмами, чувствительными к спирамицину и метронидазолу, особенно в остром и подостром периоде течения заболевания. В комплексной терапии воспалительных заболеваний ротовой полости, в том числе стоматитов, гингивитов, пиореи и периодонтита. 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