Запор, необходимость регулирования стула в медицинских целях (очищение
кишечника при подготовке к эндоскопическим и рентгенологическим исследованиям,
хирургическим вмешательствам на прямой кишке, анальном сфинктере и области,
прилегающей к нему), дисбактериоз кишечника. Печеночная энцефалопатия,
печеночная прекома и кома, гипераммониемия.
Противопоказания
Повышенная чувствительность к
лактитолу.
Дефицит лактазы, непереносимость фруктозы и галактозы, галактоземия,
синдром глюкозо-галактозной мальабсорбции.
Синдром полной или частичной
кишечной непроходимости, подозрение на органические повреждения
желудочно-кишечного тракта, абдоминальные боли и ректальные кровотечения
неясного генеза, воспалительные заболевания кишечника...
Порошок для приготовления раствора для приема внутрь.
Состав
Лактитола моногидрат - 5 г или 10 г в пакетике, 200 г или 500 г в
пластиковых контейнерах. Без вспомогательных веществ.
Описание
Белый кристаллический порошок.
Фармакотерапевтическая группа
Слабительное средство.
Фармакологические свойства
В толстом кишечнике лактитол расщепляется под действием флоры кишечника на
низкомолекулярные органические кислоты, что приводит к повышению осмотического
давления в толстом кишечнике, увеличению объема каловых масс, их размягчению,
облегчению дефекации и нормализации работы кишечника. Слабительный эффект
обычно наступает в течение 24 часов после применения препарата (отсроченность
обусловлена прохождением препарата через желудочно-кишечный тракт). В начале
курса лечения возможна задержка слабительного действия препарата, эффект может
наступить на второй или третий день его применения.
У больных с печеночной
энцефалопатией или печеночной комой (или прекомой) эффект достигается за счет
миграции аммиака из крови в толстый кишечник (благодаря снижению РН, увеличению
осмотического давления в просвете кишечника), удаления из толстой кишки задержанных
ионов аммония и других азотосодержащих токсических веществ. Лактитол подавляет
протеолитические бактерии и увеличивает количество ацидофильных бактерий, таким
образом, восстанавливая микробиом.
Фармакокинетика.
Лактитол осуществляет свой эффект только в толстом кишечнике, куда он
полностью попадает после приема внутрь. Он абсорбируется в минимальных
количествах в неизмененном виде (не более 0,5 - 2 % от принятой дозы).
Показания к применению
Запор, необходимость регулирования стула в медицинских целях (очищение
кишечника при подготовке к эндоскопическим и рентгенологическим исследованиям,
хирургическим вмешательствам на прямой кишке, анальном сфинктере и области,
прилегающей к нему), дисбактериоз кишечника. Печеночная энцефалопатия,
печеночная прекома и кома, гипераммониемия.
Противопоказания
Повышенная чувствительность к
лактитолу.
Дефицит лактазы, непереносимость фруктозы и галактозы, галактоземия,
синдром глюкозо-галактозной мальабсорбции.
Синдром полной или частичной
кишечной непроходимости, подозрение на органические повреждения
желудочно-кишечного тракта, абдоминальные боли и ректальные кровотечения
неясного генеза, воспалительные заболевания кишечника (ректоколит, регионарный
энтерит), предшествующее нарушение водно-солевого баланса.
Детский возраст до 1 года.
С осторожностью
Экспортал следует применять с осторожностью у пациентов, склонных к нарушениям водно-солевого баланса.
Применение при беременности и в период грудного вскармливания
Ввиду минимального всасывания лактитола, какого-либо неблагоприятного
воздействия на женщину и плод при применении его во время беременности не
предполагается. Препарат можно принимать во время беременности, если
потенциальная польза для матери превышает потенциальный риск для плода.
Ввиду минимального всасывания,
проникновение лактитола в грудное молоко не предполагается. Препарат можно
принимать в период грудного вскармливания, если потенциальная польза для матери
превышает потенциальный риск для ребенка.
Способ применения и дозы
Внутрь во время еды, смешивая с различными напитками (вода, чай, кофе, соки
и др.) или жидкой пищей.
При запоре и дисбактериозе. Препарат следует
принимать однократно, всю суточную дозу сразу, за один прием.
Дети 1 -6 лет —2,5 - 5 г (1/2 - 1 чайная ложка порошка) в сутки.
Дети 6 -12 лет —5 - 10 г (1 - 2 чайных ложки порошка) в сутки.
Дети 12 -16 лет —10 - 20 г (2 - 4 чайных ложки порошка) в сутки.
Взрослые: 20 г (4 чайных ложки порошка) в сутки.
Препарат должен вызывать стул
один раз в сутки; после наступления стабильного слабительного эффекта в течение
нескольких дней применения препарата, его дозу можно снизить. В ряде случаев
для получения необходимого эффекта достаточной бывает половины рекомендованной
суточной дозы:
Дети 1-6 лет - 1,25
-2,5 г (1/4 -1/2 чайной ложки порошка) в сутки.
Дети 6-12 лет – 2,5
- 5 г (1/2 - 1 чайная ложка порошка) в сутки.
Дети 12-16 лет - 5
- 10 г (1 - 2 чайных ложки порошка) в сутки.
Взрослые: 10 г (2
чайных ложки порошка) в сутки.
Минимальный курс терапии, после которого следует обратиться за консультацией
к врачу — 5 месяцев. Применение препарата у детей рекомендуется проводить под
наблюдением врача.
При регулировании стула в медицинских целях. По 20 г препарата, разведенного в 1 л воды, принимают три раза (в 12, 15
и 18 часов) накануне проведения медицинских процедур.
При печеночной энцефалопатии, печеночной прекоме и коме, гипераммониемии. Доза препарата должна быть подобрана индивидуально для каждого пациента, в
зависимости от степени выраженности заболевания и индивидуальной реакции на препарат.
Начальная суточная доза обычно составляет 0,5-0,7 г на 1 кг массы тела. Эту
дозу разделяют на три разовые дозы. Принимают во время еды. Должна быть
подобрана доза, вызывающая два «мягких» стула в сутки.
Побочное действие
В начале лечения возможно ощущение дискомфорта в животе, метеоризм и, в
редких случаях, боли в животе и вздутие живота. Эти явления, как правило,
исчезают при продолжении применения препарата, по мере адаптации к нему.
В случае применения повышенных
доз в течение длительного времени при лечении печеночной энцефалопатии у
пациента, вследствие диареи, может развиться электролитный дисбаланс.
Из-за индивидуальных различий у
некоторых пациентов возможно возникновение диареи даже при приеме рекомендуемой
дозы препарата. В этом случае необходимо уменьшить дозу препарата.
Частота побочных эффектов
классифицирована в соответствии с рекомендациями Всемирной организации
здравоохранения: очень часто - не менее 10%; часто - не менее 1%, но менее 10%;
нечасто - не менее 0,1%, но менее 1%; редко - не менее 0,01%, но менее 0,1%;
очень редко - менее 0,01%; неизвестная частота - не может быть оценена, исходя
из имеющихся данных.
Нарушения со стороны желудочно-кишечного тракта
Редко: метеоризм, боль в животе, вздутие живота, рвота, диарея.
Очень редко: тошнота, анальный зуд.
Передозировка
Симптомы: диарея, боль в животе, в редких случаях возможна рвота. Эти
явления обычно устраняются снижением дозы препарата.
Лечение: снижение дозы или
отмена препарата. Коррекция возможных нарушений водно-солевого баланса.
Взаимодействие с другими лекарственными средствами
При одновременном приеме Экспортала® с кишечнорастворимыми препаратами
рН-зависимого высвобождения следует учитывать, что лактитол понижает рН
кишечника.
Не рекомендуется применять
Экспортал® в течение двух часов после приема других лекарственных средств.
Особые указания
Лактитол имеет низкую
калорийность (2 ккал/г), не влияет на уровень глюкозы в крови и может
применяться у больных сахарным диабетом.
На протяжении всего курса
применения препарата желательно повышенное потребление жидкости.
Применение Экспортала® не
оказывает влияния на психомоторные функции, связанные с вождением автомобиля
или управлением машинами и механизмами.
Форма выпуска
Порошок для приготовления раствора для приема внутрь. По 5 г или 10 г в
однодозовые пакетики (саше), изготовленные из бумаги с полиэтиленовым покрытием
или из Буфлена - комбинированного материала на основе бумаги, алюминия и
полиэтилена, 2 пакетика (саше) соединены в 1 стрип (разделяются по перфорированной
полосе).
По 3, 6 стрипов или 6, 12
пакетиков (саше) по 5 г, или по 5, 10 стрипов или по 10, 20 пакетиков
(саше) по 10 г вместе с инструкцией по применению помещают в пачку из
картона.
По 200 или 500 г в пластиковый
контейнер. Инструкция по применению приклеивается к контейнеру.
Условия хранения
В сухом, защищенном от света и недоступном для детей месте.
Срок годности
5 лет. Не применять по истечению срока годности, указанного на упаковке.
Условия отпуска
Без рецепта.
Производитель
ООО НПО «ФармВИЛАР», Россия.
Организация, принимающая претензии потребителей
АО «Валента Фарм»
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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номер","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eЛСР-003898/07-211118\u003c/b\u003e"}}]},{"id":7,"name":"Торговое название препарата","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eЭкспортал®\u003c/b\u003e"}}]},{"id":8,"name":"Лекарственная форма","slug":"","body":[{"type":"paragraph","data":{"text":"Порошок для приготовления раствора для приема внутрь."}}]},{"id":9,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"Лактитола моногидрат - 5 г или 10 г в пакетике, 200 г или 500 г в\nпластиковых контейнерах. Без вспомогательных веществ."}}]},{"id":10,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Белый кристаллический порошок."}}]},{"id":11,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eСлабительное средство.\u003c/b\u003e"}}]},{"id":1,"name":"Фармакологические свойства","slug":"pharmacologic_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В толстом кишечнике лактитол расщепляется под действием флоры кишечника на\nнизкомолекулярные органические кислоты, что приводит к повышению осмотического\nдавления в толстом кишечнике, увеличению объема каловых масс, их размягчению,\nоблегчению дефекации и нормализации работы кишечника. Слабительный эффект\nобычно наступает в течение 24 часов после применения препарата (отсроченность\nобусловлена прохождением препарата через желудочно-кишечный тракт). В начале\nкурса лечения возможна задержка слабительного действия препарата, эффект может\nнаступить на второй или третий день его применения."}},{"type":"paragraph","data":{"text":"У больных с печеночной\nэнцефалопатией или печеночной комой (или прекомой) эффект достигается за счет\nмиграции аммиака из крови в толстый кишечник (благодаря снижению РН, увеличению\nосмотического давления в просвете кишечника), удаления из толстой кишки задержанных\nионов аммония и других азотосодержащих токсических веществ. Лактитол подавляет\nпротеолитические бактерии и увеличивает количество ацидофильных бактерий, таким\nобразом, восстанавливая микробиом."}},{"type":"paragraph","data":{"text":"\u003cb\u003eФармакокинетика.\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Лактитол осуществляет свой эффект только в толстом кишечнике, куда он\nполностью попадает после приема внутрь. Он абсорбируется в минимальных\nколичествах в неизмененном виде (не более 0,5 - 2 % от принятой дозы)."}}]},{"id":2,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Запор, необходимость регулирования стула в медицинских целях (очищение\nкишечника при подготовке к эндоскопическим и рентгенологическим исследованиям,\nхирургическим вмешательствам на прямой кишке, анальном сфинктере и области,\nприлегающей к нему), дисбактериоз кишечника. Печеночная энцефалопатия,\nпеченочная прекома и кома, гипераммониемия."}}]},{"id":3,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к\nлактитолу."}},{"type":"paragraph","data":{"text":"Дефицит лактазы, непереносимость фруктозы и галактозы, галактоземия,\nсиндром глюкозо-галактозной мальабсорбции."}},{"type":"paragraph","data":{"text":"Синдром полной или частичной\nкишечной непроходимости, подозрение на органические повреждения\nжелудочно-кишечного тракта, абдоминальные боли и ректальные кровотечения\nнеясного генеза, воспалительные заболевания кишечника (ректоколит, регионарный\nэнтерит), предшествующее нарушение водно-солевого баланса."}},{"type":"paragraph","data":{"text":"Детский возраст до 1 года."}}]},{"id":12,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Экспортал следует применять с осторожностью у пациентов, склонных к нарушениям водно-солевого баланса."}}]},{"id":13,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Ввиду минимального всасывания лактитола, какого-либо неблагоприятного\nвоздействия на женщину и плод при применении его во время беременности не\nпредполагается. Препарат можно принимать во время беременности, если\nпотенциальная польза для матери превышает потенциальный риск для плода."}},{"type":"paragraph","data":{"text":"Ввиду минимального всасывания,\nпроникновение лактитола в грудное молоко не предполагается. Препарат можно\nпринимать в период грудного вскармливания, если потенциальная польза для матери\nпревышает потенциальный риск для ребенка."}}]},{"id":14,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь во время еды, смешивая с различными напитками (вода, чай, кофе, соки\nи др.) или жидкой пищей."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри запоре и дисбактериозе\u003c/i\u003e. Препарат следует\nпринимать однократно, всю суточную дозу сразу, за один прием."}},{"type":"paragraph","data":{"text":"Дети 1 -6 лет —2,5 - 5 г (1/2 - 1 чайная ложка порошка) в сутки."}},{"type":"paragraph","data":{"text":"Дети 6 -12 лет —5 - 10 г (1 - 2 чайных ложки порошка) в сутки."}},{"type":"paragraph","data":{"text":"Дети 12 -16 лет —10 - 20 г (2 - 4 чайных ложки порошка) в сутки."}},{"type":"paragraph","data":{"text":"Взрослые: 20 г (4 чайных ложки порошка) в сутки."}},{"type":"paragraph","data":{"text":"Препарат должен вызывать стул\nодин раз в сутки; после наступления стабильного слабительного эффекта в течение\nнескольких дней применения препарата, его дозу можно снизить. В ряде случаев\nдля получения необходимого эффекта достаточной бывает половины рекомендованной\nсуточной дозы:"}},{"type":"paragraph","data":{"text":"Дети 1-6 лет - 1,25\n-2,5 г (1/4 -1/2 чайной ложки порошка) в сутки."}},{"type":"paragraph","data":{"text":"Дети 6-12 лет – 2,5\n- 5 г (1/2 - 1 чайная ложка порошка) в сутки."}},{"type":"paragraph","data":{"text":"Дети 12-16 лет - 5\n- 10 г (1 - 2 чайных ложки порошка) в сутки."}},{"type":"paragraph","data":{"text":"Взрослые: 10 г (2\nчайных ложки порошка) в сутки."}},{"type":"paragraph","data":{"text":"Минимальный курс терапии, после которого следует обратиться за консультацией\nк врачу — 5 месяцев. Применение препарата у детей рекомендуется проводить под\nнаблюдением врача."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри регулировании стула в медицинских целях\u003c/i\u003e. По 20 г препарата, разведенного в 1 л воды, принимают три раза (в 12, 15\nи 18 часов) накануне проведения медицинских процедур."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри печеночной энцефалопатии, печеночной прекоме и коме, гипераммониемии. \u003c/i\u003eДоза препарата должна быть подобрана индивидуально для каждого пациента, в\nзависимости от степени выраженности заболевания и индивидуальной реакции на препарат.\nНачальная суточная доза обычно составляет 0,5-0,7 г на 1 кг массы тела. Эту\nдозу разделяют на три разовые дозы. Принимают во время еды. Должна быть\nподобрана доза, вызывающая два «мягких» стула в сутки."}}]},{"id":4,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В начале лечения возможно ощущение дискомфорта в животе, метеоризм и, в\nредких случаях, боли в животе и вздутие живота. Эти явления, как правило,\nисчезают при продолжении применения препарата, по мере адаптации к нему."}},{"type":"paragraph","data":{"text":"В случае применения повышенных\nдоз в течение длительного времени при лечении печеночной энцефалопатии у\nпациента, вследствие диареи, может развиться электролитный дисбаланс."}},{"type":"paragraph","data":{"text":"Из-за индивидуальных различий у\nнекоторых пациентов возможно возникновение диареи даже при приеме рекомендуемой\nдозы препарата. В этом случае необходимо уменьшить дозу препарата."}},{"type":"paragraph","data":{"text":"Частота побочных эффектов\nклассифицирована в соответствии с рекомендациями Всемирной организации\nздравоохранения: очень часто - не менее 10%; часто - не менее 1%, но менее 10%;\nнечасто - не менее 0,1%, но менее 1%; редко - не менее 0,01%, но менее 0,1%;\nочень редко - менее 0,01%; неизвестная частота - не может быть оценена, исходя\nиз имеющихся данных."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного тракта\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eРедко: \u003c/i\u003eметеоризм, боль в животе, вздутие живота, рвота, диарея."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОчень редко:\u003c/i\u003e тошнота, анальный зуд."}}]},{"id":5,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы: диарея, боль в животе, в редких случаях возможна рвота. Эти\nявления обычно устраняются снижением дозы препарата."}},{"type":"paragraph","data":{"text":"Лечение: снижение дозы или\nотмена препарата. Коррекция возможных нарушений водно-солевого баланса."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном приеме Экспортала® с кишечнорастворимыми препаратами\nрН-зависимого высвобождения следует учитывать, что лактитол понижает рН\nкишечника."}},{"type":"paragraph","data":{"text":"Не рекомендуется применять\nЭкспортал® в течение двух часов после приема других лекарственных средств."}}]},{"id":6,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Лактитол имеет низкую\nкалорийность (2 ккал/г), не влияет на уровень глюкозы в крови и может\nприменяться у больных сахарным диабетом."}},{"type":"paragraph","data":{"text":"На протяжении всего курса\nприменения препарата желательно повышенное потребление жидкости."}},{"type":"paragraph","data":{"text":"Применение Экспортала® не\nоказывает влияния на психомоторные функции, связанные с вождением автомобиля\nили управлением машинами и механизмами."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Порошок для приготовления раствора для приема внутрь. По 5 г или 10 г в\nоднодозовые пакетики (саше), изготовленные из бумаги с полиэтиленовым покрытием\nили из Буфлена - комбинированного материала на основе бумаги, алюминия и\nполиэтилена, 2 пакетика (саше) соединены в 1 стрип (разделяются по перфорированной\nполосе)."}},{"type":"paragraph","data":{"text":"По 3, 6 стрипов или 6, 12\nпакетиков (саше) по 5 г, или по 5, 10 стрипов или по 10, 20 пакетиков\n(саше) по 10 г вместе с инструкцией по применению помещают в пачку из\nкартона."}},{"type":"paragraph","data":{"text":"По 200 или 500 г в пластиковый\nконтейнер. Инструкция по применению приклеивается к контейнеру."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В сухом, защищенном от света и недоступном для детей месте."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"5 лет. 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