Милдронат Раствор, 10 шт, 5 мл, 100 мг/мл, для инъекций

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Благодаря этим\nсвойствам МИЛДРОНАТ используют для лечения различных\nнарушений деятельности сердечно-сосудистой системы, кровоснабжения головного мозга,\nа также для повышения физической и умственной работоспособности. В\nрезультате снижения концентрации карнитина усиленно синтезируется\nгамма-бутиробетаин, обладающий вазодилатирующими свойствами. В случае\nострого ишемического повреждения миокарда МИЛДРОНАТ замедляет\nобразование некротической зоны, укорачивает реабилитационный период. При\nсердечной недостаточности повышает сократимость миокарда, увеличивает\nтолерантность к физической нагрузке, снижает частоту приступов стенокардии. При\nострых и хронических ишемических нарушениях мозгового кровообращения МИЛДРОНАТ улучшает\nциркуляцию крови в очаге ишемии, способствует перераспределению крови в пользу\nишемизированного участка. 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Препарат\nможет давать положительный результат при проведении допинг контроля (см. раздел\n«Особые указания»)."}},{"type":"paragraph","data":{"text":"Синдром абстиненции при\nхроническом алкоголизме (в комбинации со специфической терапией алкоголизма)."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Гиперчувствительность к компонентам препарата, повышение внутричерепного давления (при\nнарушении венозного оттока, внутричерепных опухолях), возраст до 18 лет\n(эффективность и безопасность не установлены), беременность, период кормления\nгрудью."}}]},{"id":14,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"При заболеваниях печени и/или почек."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Безопасность применения у беременных женщин не\nизучена, поэтому, во избежание возможного неблагоприятного воздействия на плод,\nего применение противопоказано."}},{"type":"paragraph","data":{"text":"Выделение препарата МИЛДРОНАТ с молоком и его влияние\nна состояние здоровья новорожденного не изучены, поэтому, при необходимости\nприменения, следует прекратить грудное вскармливание."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Ввиду возможного\nразвития возбуждающего эффекта, рекомендуется применять в первой половине\nдня."}},{"type":"paragraph","data":{"text":"МИЛДРОНАТ вводят\nвнутримышечно (в/м), внутривенно (в/в) и парабульбарно. Способ введения, дозы и\nпродолжительность курса лечения устанавливают индивидуально, в зависимости от\nпоказаний, тяжести состояния и др."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e1. \u003c/i\u003e\u003c/b\u003e\u003cb\u003e\u003ci\u003eСердечно-сосудистые заболевания\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"В составе комплексной терапии:"}},{"type":"paragraph","data":{"text":"- ишемической болезни сердца\n(инфаркт миокарда) в/в струйно по 0,5-1,0 г в день (5‑10 мл препарата МИЛДРОНАТ);"}},{"type":"paragraph","data":{"text":"- ишемической болезни\nсердца (стабильная стенокардия); хронической сердечной недостаточности и кардиомиопатии на фоне\nдисгормональных нарушений в/в струйно по 0,5-1,0 г в день (5-10 мл препарата МИЛДРОНАТ) или в/м по 0,5 г 1-2 раза в сутки, курс\nлечения 10‑14 дней, с последующим переходом на прием внутрь. Общий курс лечения\n4‑6 недель."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e2. Нарушение мозгового кровообращения\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"В составе комплексной терапии в острой фазе по 0,5 г (5 мл препарата МИЛДРОНАТ) 1 раз в день в/в в течение 10 дней, переходя на прием\nвнутрь по 0,5‑1 г. Общий курс лечения –\n4-6 недель."}},{"type":"paragraph","data":{"text":"При хронической недостаточности мозгового\nкровообращения (дисциркуляторной энцефалопатии) по 0,5 г\n(5 мл препарата МИЛДРОНАТ)\nв/м или в/в 1 раз в день в течение 10 дней, затем по\n0,5 г внутрь. Общий курс лечения – 4‑6 недель."}},{"type":"paragraph","data":{"text":"Повторные курсы (обычно 2-3 раза в год) возможны\nпосле консультации с врачом."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e3.\u003c/i\u003e\u003c/b\u003e\u003cb\u003e\u003ci\u003e \u003c/i\u003e\u003c/b\u003e\u003cb\u003e\u003ci\u003eОфтальмопатология \u003c/i\u003e\u003c/b\u003e(\u003ci\u003eгемофтальм и кровоизлияния в сетчатку различной\nэтиологии, тромбоз центральной вены сетчатки и ее ветвей, ретинопатии различной\nэтиологии (диабетическая, гипертоническая\u003c/i\u003e))."}},{"type":"paragraph","data":{"text":"По 0,05 г (0,5 мл\nпрепарата МИЛДРОНАТ) парабульбарно\nв течение 10 дней. В том числе применяется в составе\nкомбинированной терапии."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e4. Умственные и физические перегрузки\u003c/i\u003e\u003c/b\u003e\u003ci\u003e\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 0,5 г (5 мл\nпрепарата МИЛДРОНАТ) в/м\nили в/в 1 раз в день. Курс лечения – 10‑14 дней. При необходимости лечение повторяют через 2-3 недели."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e5. Хронический алкоголизм\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"По 0,5 г (5 мл\nпрепарата МИЛДРОНАТ) в/м\nили в/в 2 раза в день. Курс лечения – 7‑10 дней."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В зависимости от частоты возникновения выделяют следующие группы нежелательных\nпобочных реакций по ВОЗ: очень часто (> 1/10), часто (> 1/100, < 1/10),\nнечасто (> 1/1000, < 1/100), редко (> 1/10000, < 1/1000), очень редко\n(< 1/10000), включая отдельные сообщения, частота неизвестна – не может быть\nопределена по имеющимся данным."}},{"type":"paragraph","data":{"text":"Редко – аллергические реакции (покраснение,\nвысыпания, зуд, отек), а также диспептические явления, тахикардия, снижение или\nповышение артериального давления, возбуждение."}},{"type":"paragraph","data":{"text":"Очень редко – эозинофилия, общая слабость.\u003cb\u003e\u003c/b\u003e"}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы: снижение артериального давления,\nсопровождающееся головной болью, тахикардией, головокружением и общей\nслабостью."}},{"type":"paragraph","data":{"text":"Лечение: симптоматическое."}},{"type":"paragraph","data":{"text":"МИЛДРОНАТ малотоксичен и не вызывает нежелательных реакций,\nопасных для здоровья пациентов."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Можно сочетать с антиангинальными средствами,\nантикоагулянтами, антиагрегантами, антиаритмическими средствами, диуретиками,\nбронхолитиками. "}},{"type":"paragraph","data":{"text":"Усиливает действие сердечных гликозидов."}},{"type":"paragraph","data":{"text":"Ввиду возможного развития умеренной тахикардии и\nартериальной гипотензии, следует соблюдать осторожность при комбинации с нитроглицерином, нифедипином,\nальфа-адреноблокаторами, другими гипотензивными средствами и\nпериферическими вазодилататорами, так как МИЛДРОНАТ усиливает их действие."}}]},{"id":9,"name":"Особые указания","slug":"","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Многолетний опыт лечения острого инфаркта миокарда\nи нестабильной стенокардии в кардиологических\nотделениях показывает, что МИЛДРОНАТ не является\nпрепаратом I  ряда при остром коронарном синдроме и\nего применение не является остро необходимым."}},{"type":"paragraph","data":{"text":"С 1 января\n2016 года мельдоний включен в список запрещенных веществ Всемирного\nантидопингового агентства."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Нет данных о неблагоприятном воздействии препарата\nМИЛДРОНАТ на скорость психомоторной реакции."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Раствор для внутримышечного, внутривенного и парабульбарного\nвведения, 100 мг/мл."}},{"type":"paragraph","data":{"text":"По 5 мл в ампуле из бесцветного\nстекла I гидролитического класса с линией или точкой\nразлома."}},{"type":"paragraph","data":{"text":"По 5 ампул в ячейковой\nупаковке из поливинилхлоридной пленки или из полиэтилентерефталатной пленки без покрытия (поддон)."}},{"type":"paragraph","data":{"text":"По 2 или 4 ячейковые упаковки (поддона) вместе с\nинструкцией по применению в пачке из картона. На пачке может быть нанесен\nстикер для контроля первого вскрытия."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Не замораживать! "}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте!"}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"5 лет."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности,\nуказанного на упаковке."}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"-          \nЗАО «Сантоника»,"}},{"type":"paragraph","data":{"text":"ул. Вейверю д. 134Б, Каунас, Литва, 46353"}},{"type":"paragraph","data":{"text":"-          \nЭйч Би Эм\nФарма с.р.о."}},{"type":"paragraph","data":{"text":"Ул. Склабинска, 30, Мартин, 036 80,\nСловакия"}}]},{"id":22,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО «Гриндекс Рус»."}},{"type":"paragraph","data":{"text":"Россия, 117556, г. Москва, Варшавское\nшоссе, д. 74, корп. 3, 5 этаж"}},{"type":"paragraph","data":{"text":"Телефон:+7 (495) 7716505*"}},{"type":"paragraph","data":{"text":"Факс: +7 (499) 6103963"}},{"type":"paragraph","data":{"text":"Электронная почта: office@grindeks.ru"}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"ФармакодинамикаМельдоний (МИЛДРОНАТ) – структурный аналог гамма-бутиробетаина – вещества, которое находится в каждой клетке организма человека.В условиях повышенной нагрузки МИЛДРОНАТ восстанавливает равновесие между доставкой и потребностью клеток в кислороде, устраняет накопление токсических продуктов обмена в клетках, защищая их от повреждения; оказывает также тонизирующее влияние. В результате его применения организм приобретает способность выдерживать нагрузку и быстро восстанавливать энергетические резервы. Благодаря этим свойствам МИЛДРОНАТ используют для лечения различных нарушений деятельности сердечно-сосудистой системы, кровоснабжения головного мозга, а также для повышения физической и умственной работоспособности. В результате снижения концентрации карнитина усиленно синтезируется гамма-бутиробетаин, обладающий вазодилатирующими свойствами. В случае острого ишемического повреждения миокарда МИЛДРОНАТ замедляет образование некротической зоны, укорачивает реабилитационный период. При сердечной недостаточности повышает сократимость миокарда, увеличивает толерантность к физической нагрузке, снижает частоту приступов стенокардии. При острых и хронических ишемических нарушениях мозгового кровообращения МИЛДРОНАТ улучшает циркуляцию крови в очаге ишемии, способствует перераспределению крови в пользу ишемизированного участка. Препарат устраняет функциональные нарушения нервной системы у больных хроническим алкоголизмом при синдроме абстиненции.ФармакокинетикаБиодоступность препарата после внутривенного введения равна 100 %. Максимальная концентрация в плазме крови достигается сразу после его введения. Метаболизируется в организме с образованием двух основных метаболитов, которые выводятся почками. Период полувыведения (T1/2) составляет 3 – 6 часов.","substance":[{"id":726,"title":"Мельдоний","title_latin":"Meldonium","slug":"meldoniy_726"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":false,"comments":null,"image_alt":"Милдронат - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/89860/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/89860/share_default/"}},"diseases":[{"id":"425","title":"Другие виды недостаточности питания","slug":"425-drugie_vidy_nedostatochnosti_pitaniya"},{"id":"475","title":"Абстинентное состояние","slug":"475-abstinentnoe_sostoyf103"},{"id":"557","title":"Преходящие транзиторные церебральные ишемические приступы [атаки] и родственные синдромы","slug":"557-prehodyaschie_tranzitornye_tserebralnye_ishemicheskie_pristupy_ataki_i_rodstvennye_sindromy"},{"id":"654","title":"Окклюзии сосудов 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