Милдронат Капсулы, 40 шт, 250 мг, для приема внутрь, для повышения работоспособности

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Однако у восприимчивых\nпациентов, а также в случаях превышения рекомендуемой дозы возможно\nвозникновение нежелательных реакций."}},{"type":"paragraph","data":{"text":"Нежелательные лекарственные реакции\nсгруппированы по системно-органным классам в соответствии со следующей градацией частоты: очень часто (≥ 1/10), часто"}},{"type":"paragraph","data":{"text":"(≥ 1/100 и < 1/10), нечасто (≥ 1/1000 и < 1/100), редко (≥ 1/10 000 и\n< 1/1000) и очень редко (< 1/10\n000), частота неизвестна — по имеющимся данным частоту оценить\nневозможно."}},{"type":"list","data":{"style":"unordered","items":["Со стороны\nкрови и лимфатической системы"]}},{"type":"paragraph","data":{"text":"Частота неизвестна: эозинофилия."}},{"type":"list","data":{"style":"unordered","items":["Со стороны иммунной системы"]}},{"type":"paragraph","data":{"text":"Часто: аллергические реакции (покраснение кожи, высыпания, зуд, припухлость)."}},{"type":"list","data":{"style":"unordered","items":["Со стороны\nсердца "]}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e\u003c/i\u003e\u003c/b\u003eОчень\nредко: тахикардия. "}},{"type":"list","data":{"style":"unordered","items":["Со стороны\nсосудов"]}},{"type":"paragraph","data":{"text":"Очень\nредко: снижение артериального давления. "}},{"type":"list","data":{"style":"unordered","items":["Со\nстороны желудочно-кишечного тракта "]}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e\u003c/i\u003e\u003c/b\u003eЧасто: диспептические явления"}},{"type":"list","data":{"style":"unordered","items":["Со стороны\nнервной системы"]}},{"type":"paragraph","data":{"text":"Часто: головные боли;"}},{"type":"paragraph","data":{"text":"Частота неизвестна: возбуждение."}},{"type":"list","data":{"style":"unordered","items":["Общие нарушения"]}},{"type":"paragraph","data":{"text":"Частота неизвестна: общая слабость."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли любые из указанных в\nинструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные\nэффекты, не указанные в\nинструкции, \u003cb\u003eсообщите об этом врачу\u003c/b\u003e.\u003c/i\u003e"}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"О случаях\nпередозировки мельдонием не сообщалось. Препарат\nмалотоксичен и не вызывает тяжелых\nнежелательных реакций."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\u003c/i\u003e: снижение артериального давления,\nсопровождающееся головной болью,\nтахикардией, головокружением и общей слабостью."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение\u003c/i\u003e: симптоматическое."}},{"type":"paragraph","data":{"text":"При тяжелой передозировке необходимо контролировать функции печени\nи почек."}}]},{"id":9,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Мельдоний допускается одновременно применять с нитратами пролонгированного действия и другими\nантиангинальными средствами, сердечными гликозидами и"}},{"type":"paragraph","data":{"text":"мочегонными препаратами. Также его можно комбинировать с антикоагулянтами, антиагрегантами, антиаритмическими средствами и другими препаратами, улучшающими микроциркуляцию."}},{"type":"paragraph","data":{"text":"Мельдоний может усиливать\nдействие нитроглицерина, нифедипина, бета- адреноблокаторов,\nдругих гипотензивных средств и периферических вазодилататоров. Одновременное применение препарата\nвместе с другими препаратами мельдония не допускается, поскольку\nможет увеличиться риск возникновения нежелательных реакций."}}]},{"id":10,"name":"Особые указания","slug":"","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Пациентам с хроническими заболеваниями печени и почек следует\nсоблюдать осторожность при длительном применении препарата. При необходимости длительного (более месяца) применения препарата необходимо\nпроконсультироваться со специалистом.\nПрепарат может давать положительный результат при проведении допинг контроля."}}]},{"id":25,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Нет данных о неблагоприятном влиянии на способность управления транспортным средством и выполнения потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций."}}]},{"id":26,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы 250 мг."}},{"type":"paragraph","data":{"text":"По 10 капсул в контурной\nячейковой упаковке из пленки поливинилхлоридной с поливинилиденхлоридным покрытием\nи алюминиевой фольги.\nПо 2 (4) контурные ячейковые\nупаковки вместе с инструкцией по применению в картонную пачку."}},{"type":"paragraph","data":{"text":"На пачке может быть нанесен стикер для контроля\nпервого вскрытия."}}]},{"id":11,"name":"Условия хранения","slug":"storage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Хранить при\nтемпературе не выше 25 °С. Хранить в недоступном для детей месте."}}]},{"id":12,"name":"Срок годности","slug":"expiry_date","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"4 года."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности, указанного на упаковке."}}]},{"id":13,"name":"Условия отпуска","slug":"release_condition","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":27,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"АО «Гриндекс».\nУл. Крустпилс, 53, Рига, LV-1057, Латвия Телефон: +371 67083205"}},{"type":"paragraph","data":{"text":"Факс: +371 67083505"}},{"type":"paragraph","data":{"text":"Электронная почта: \u003ca href=\"mailto:grindeks@grindeks.lv\"\u003egrindeks@grindeks.lv\u003c/a\u003e"}}]},{"id":28,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО «Гриндекс Рус»."}},{"type":"paragraph","data":{"text":"Россия, 117556, г. Москва, Варшавское шоссе,\nд. 74, корп. 3, 5 этаж"}},{"type":"paragraph","data":{"text":"Телефон:+7 (495) 7716505*"}},{"type":"paragraph","data":{"text":"Факс: +7 (499) 6103963"}},{"type":"paragraph","data":{"text":"Электронная почта:\n\u003ca href=\"mailto:office@grindeks.ru\"\u003eoffice@grindeks.ru\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"ФармакодинамикаМельдоний является структурным аналогом предшественника карнитина - гамма- бутиробетаина (ГББ), вещества, которое находится в каждой клетке организма человека. В условиях повышенной нагрузки мельдоний восстанавливает равновесие между доставкой и потребностью клеток в кислороде, устраняет накопление токсических продуктов обмена в клетках, защищая их от повреждения; оказывает также тонизирующее влияние. В результате его применения повышается устойчивость организма к нагрузкам и способность быстро восстанавливать энергетические резервы. Препарат обладает стимулирующим действием на центральную нервную систему (ЦНС) — повышение двигательной активности и физической выносливости. Благодаря этим свойствам МИЛДРОНАТ используют в том числе для повышения физической и умственной работоспособности.ФармакокинетикаПосле приема внутрь препарат быстро всасывается, биодоступность – 78 %. Максимальная концентрация (Cmax) в плазме крови достигается через 1-2 часа после приема внутрь. Метаболизируется в организме главным образом в печени с формированием двух основных метаболитов, которые выводятся почками. Период полувыведения (T1/2) при приеме внутрь зависит от дозы, составляет 3-6 часов. 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